In-line Process Analysis Of Residual Moisture In A Fluid Bed Granulator–Dryer Using NIR Spectroscopy It is also used to maintain a consistent average particle size distribution (PSD) for the formulation, thus allowing for a better quality mixture when creating solid dosage forms such as tablets and capsules. Size reduction is used to increase surface area and improve formulation dissolution properties. Milling And Micronization Of Pharmaceutical Powders This is unfortunate since it is at least as fundamentally important as particle size in determining the behaviour of particulate materials, especially those with sizes in the colloidal range below a micrometer. Zeta Potential In Pharmaceutical FormulationĪlthough particle size and its measurement are intuitively familiar to particle technologists, the concept of zeta potential is less widely understood and applied. Also, check out product information from HORIBA Instruments and Key International. In this section, be sure to read the article from Niro on troubleshooting fluid bed granulation and the brochure from Glatt Air Techniques that provides innovative technologies for granules and pellets. Located in the right-hand column is our Spotlight On Granulation And Particle Sizing section, which includes several brochures and articles regarding this topic. In our editorial section, you can also read about using NIR spectroscopy during the granulation process, milling technologies used in cell culture manufacturing, and how a new technology solved an old particle size analysis problem. K-Tron Process Group provides an article in this issue that describes the milling and micronization on pharmaceutical powders and how it can be used to maintain average particle size distribution. Our featured white paper from Malvern Instruments provides an overview of zeta potential and its importance in determining the behavior of particulate materials. Although particle size and its measurement are intuitively familiar to particle technologists, the concept of zeta potential is less widely understood and applied. Welcome back to the Pharmaceutical Online newsletter and our spotlight on granulation and particle sizing. ACT NOW! Offer valid for orders up to December 15, 2007. Up to 40% off - offer applies to all brands of particle sizers (not just Malvern). Malvern's trade-in program offers and unprecedented opportunity to own a new Malvern. Malvern's Particle Size Trade-In Program will help you build a compelling case for your management.
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